The nicotine content of many 2ml nicotine pods for multi pod devices is equivalent to a pack of 20 cigarettes. If you don't smoke, don't vape. And if you are smoking Public The amount of nicotine in an e cigarette can vary greatly. Youth may intake nicotine levels that are equivalent to multiple packs of cigarettes. To learn more about the highly addictive News Quick KnowHow Many Cigarettes are in a Disposable Vape? Vaping vs. Smoking: What's the Nicotine Equivalent? Curious about how vaping compares to smoking? Let's break it down! Disposable Vapes: A typical disposable vape with around 600 puffs can E Cigarettes (Vapes) Smoking and Tobacco Use CDC