Tylenol Avoid or Not to Avoid? Acetaminophen (Tylenol) can deplete glutathione, your body's most important detox antioxidant. This matters even more if your child has an MTHFR gene mutation, which Is Tylenol Safe During Pregnancy? Understanding Risk Factors Seeking Health Could Tylenol be making your child's health worse? Acetaminophen is widely used for pain and fever relief, but research suggests it depletes glutathione, a powerful antioxidant essential for immune function, View of Acetaminophen, the missing anion gap in the patient with metabolic acidosis The Southwest journal of medicine 7 Things to Avoid When Taking Glutathione Core Med Science