Glutathione Depletion and Stalwart Anticancer Activity of Metallotherapeutics Inducing Programmed Cell Death: Opening a New Window for Cancer Therapy ACS Omega Sulforaphane for Liver Health Sulforaphane is a food derived compound with a few core mechanisms. Nrf2 Activation for Phase II support being the primary mechanism. Increased glutathione production Increased phase II enzymes (GST, Sulforaphane: Studies, Genetic Connections Sulforaphane Induces Oxidative Stress and Death by p53 Independent Mechanism: Implication of Impaired Glutathione Recycling PLOS One Enhanced sulforaphane accumulation in fresh cut broccoli via exogenous glutathione mediated modulation of the AsA GSH cycle ScienceDirect